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reinstalling - "Only a single instance of this application can run"

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I had to uninstall Adobe Reader some months back and ever since have been unable to reinstall. I get through the first couple download steps, and click yes to "allow the following program to make changes to this computer", but then it all closes down and sometimes I get the "Only a single instance of this application can run" box pop up. I googled that error message and have spent hours trying every tip on how to resolve it on various message boards but nothing works and I really need to be able to open pdfs again. Thanks for any help you can provide.


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